Translational Research
Volume 152, Issue 2 , Pages 81-87 , August 2008

Growth factors expression in patients with erosive esophagitis

Received 7 April 2008 ,Revised 28 May 2008 ,Accepted 30 May 2008.

References 

  1. Luo JC, Shin VY, Liu ESL, et al. Non-ulcerogenic dose of dexamethasone delays gastric ulcer healing in rats. J Pharmacol Exp Ther. 2003;307:692–698
  2. Luo JC, Shin VY, Liu ESL, et al. Dexamethasone delays ulcer healing by inhibition of angiogenesis in rat stomachs. Eur J Pharmacl. 2004;485:275–281
  3. Tarnawski AS. Cellular and molecular mechanisms of gastrointestinal ulcer healing. Dig Dis Sci. 2005;50(suppl):S24–S33
  4. Milani S, Calabro A. Role of growth factors and their receptors in gastric ulcer healing. Microsc Res Techniq. 2001;53:360–371
  5. Szabo S, Vincze A. Growth factors in ulcer healing (Lesions from recent studies). J Physiol (Paris). 2000;94:77–81
  6. Peskar BM, Maricic N, Gretzer B, Schuligoi R, Schmassmann A. Role of cyclooxygenase-2 in gastric mucosal defense. Life Sci. 2001;69:2993–3003
  7. Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R Global Consensus Group. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 2006;101:1900–1920
  8. Moayyedi P, Talley N. Gastro-esophageal reflux disease. Lancet. 2006;367:2086–2100
  9. Orr WC, Allen ML, Robinson M. The pattern of noctural and diurnal esophageal acid exposure in the pathogenesis of erosive mucosal damage. Am J Gastroenterol. 1994;89:509–512
  10. Baatar D, Kawanaka H, Szabo IL, et al. Esophageal ulceration activates keratinocyte growth factor and its receptor in rats: implications for ulcer healing. Gastroenterology. 2002;122:458–468
  11. Baatar D, Jones MK, Pai R, et al. Selective cyclooxygenase-2 block delays healing of esophageal ulcers in rats and inhibits ulceration-induction and extracellular signal-regulated kinase 2 activation. Am J Pathol. 2002;160:1963–1972
  12. Baatar D, Jones MK, Tsugawa K, et al. Esophageal ulceration triggers expression of hypoxia-inducible factor-1α and activates vascular endothelial growth factor gene. Am J Pathol. 2002;161:1449–1457
  13. Fujiwara Y, Higuchi K, Hamaguchi M, et al. Increased expression of transforming growth factor-alpha and epidermal growth factor receptors in rat chronic reflux esophagitis. J Gastroenterol Hepatol. 2004;19:521–527
  14. Armstrong D, Bennett JR, Blum AL, et al. The endoscopic assessment of esophagitis: a progress report on observer agreement. Gastroenterology. 1996;111:85–92
  15. Yoshida N, Uchiyama K, Kuroda M, et al. Interleukin-8 expression in the esophageal mucosa of patients with gastroesophageal reflux disease. Scand J Gastroenterol. 2004;9:816–822
  16. Oh DS, DeMeester SR, Vallbohmer D, et al. Reduction of interleukin-8 gene expression in reflux esophagitis and Barrett's esophagus with antireflux surgery. Arch Surg. 2007;142:554–560
  17. Vallbohmer D, DeMeester SR, Oh DS, et al. Antireflux surgery normalizes cyclooxygenase-2 espression in squamous epithelium of the distal esophagus. Am J Gastroenterol. 2006;101:1458–1466
  18. Brzozowski T, Konturek PC, Konturek SJ, et al. Effect of local application of growth factors on gastric ulcer healing and mucosal expression of cyclooxygenase-1 and -2. Digestion. 2001;64:15–29
  19. Schmassmann A. Mechanisms of ulcer healing and effects of nonsteroidial anti-inflammatory drugs. Am J Med. 1998;104:43S–51S
  20. Mizuno H, Sakamoto C, Matsuda K, et al. Introduction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology. 1997;112:387–397

 Supported by Grant V97C1-011 from Taipei Veteran General Hospital, Taipei, Taiwan.

PII: S1931-5244(08)00156-4

doi: 10.1016/j.trsl.2008.05.010

Translational Research
Volume 152, Issue 2 , Pages 81-87 , August 2008

Article Tools

* Image Usage & Resolution