« Previous
Next »
Translational Research
Volume 152, Issue 6
, Pages 257-264
, December 2008
Evolution of Pseudomonas aeruginosa type III secretion in cystic fibrosis: a paradigm of chronic infection
References
- . Impact of previous antimicrobial therapy on the etiology and outcome of ventilator-associated pneumonia. Chest. 1993;104:1230–1235
- . Health care-associated pneumonia and community-acquired pneumonia: a single-center experience. Antimicrob Agents Chemother. 2007;51:3568–3573
- . Evaluation of outcome for intubated patients with pneumonia due to Pseudomonas aeruginosa. Clin Infect Dis. 1996;23:973–978
- Role of flagella in pathogenesis of Pseudomonas aeruginosa pulmonary infection. Infect Immun. 1998;66:43–51
- . Intratracheal immunization with pili protein protects against mortality associated with Pseudomonas aeruginosa pneumonia in mice. FEMS Immunol Med Microbiol. 2006;47:107–115
- The Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils. Infect Immun. 2003;71:5785–5793
- . Subcellular localization of Pseudomonas pyocyanin cytotoxicity in human lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2003;284:L420–L430
- . Pyoverdin is essential for virulence of Pseudomonas aeruginosa. Infect Immun. 1996;64:518–523
- Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia. J Clin Invest. 1999;104:743–750
- . The exoenzyme S regulon of Pseudomonas aeruginosa. Mol Microbiol. 1997;26:621–629
- Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections. J Infect Dis. 2001;183:1767–1774
- Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa. Crit Care Med. 2002;30:521–528
- . Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa. Microbiology. 2001;147:2659–2669
- . Pseudomonas aeruginosa ExoS and ExoT. Rev Physiol Biochem Pharmacol. 2004;152:79–92
- . ExoU is a potent intracellular phospholipase. Mol Microbiol. 2004;53:1279–1290
- . The changing epidemiology of cystic fibrosis. J Pediatr. 1993;122:1–9
- . Phenotypic conversion of Pseudomonas aeruginosa in cystic fibrosis. J Clin Microbiol. 1990;28:1143–1146
- Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis. J Infect Dis. 2001;183:444–452
- Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc Natl Acad Sci U S A. 2006;103:8487–8492
- . Pseudomonas aeruginosa cystic fibrosis clinical isolates produce exotoxin A with altered ADP-ribosyltransferase activity and cytotoxicity. Microbiology. 2000;146:1891–1899
- Study of pyoverdine type and production by Pseudomonas aeruginosa isolated from cystic fibrosis patients: prevalence of type II pyoverdine isolates and accumulation of pyoverdine-negative mutations. Arch Microbiol. 2001;175:384–388
- . Heterogeneity of biofilms formed by nonmucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis. J Clin Microbiol. 2005;43:5247–5255
- . Flagella and motility alterations in Pseudomonas aeruginosa strains from patients with cystic fibrosis: relationship to patient clinical condition. Infect Immun. 1985;50:577–582
- . Epidemiology of chronic Pseudomonas aeruginosa infections in cystic fibrosis. J Infect Dis. 1994;170:1616–1621
- . Outcomes of adults with cystic fibrosis infected with antibiotic-resistant Pseudomonas aeruginosa. Respiration. 2006;73:27–33
- Type III secretion phenotypes of Pseudomonas aeruginosa strains change during infection of individuals with cystic fibrosis. J Clin Microbiol. 2004;42:5229–5237
- Identification of Pseudomonas aeruginosa genes required for epithelial cell injury. Mol Microbiol. 1997;24:1249–1262
- . Exoenzyme S: an ADP-ribosyltransferase produced by Pseudomonas Aeruginosa. In: Smulson MST editors. Novel ADP-ribosylation of regulatory enzymes and proteins. Elsevier/North Holland Inc: Amsterdam, the Netherlands; 1980;p. 425–433
- . Evolving stealth: genetic adaptation of Pseudomonas aeruginosa during cystic fibrosis infections. Proc Natl Acad Sci U S A. 2006;103:8305–8306
- Secretion of the toxin ExoU is a marker for highly virulent Pseudomonas aeruginosa isolates obtained from patients with hospital-acquired pneumonia. J Infect Dis. 2003;188:1695–1706
- Effect of anti-PcrV antibody in a murine chronic airway Pseudomonas aeruginosa infection model. Eur Respir J. 2007;29:965–968
Supported by the Cystic Fibrosis Foundation Therapeutics, Inc. (to A.R.H.), Grant K02 AI065615 from the National Institutes of Health (to A.R.H.), Grant NHLBI/NCRR 1K12RR017707-02 (to M.J.), and Grant M01 RR-00048 (to M.J.).
PII: S1931-5244(08)00244-2
doi: 10.1016/j.trsl.2008.10.003
© 2008 Mosby, Inc. All rights reserved.
« Previous
Next »
Translational Research
Volume 152, Issue 6
, Pages 257-264
, December 2008
