Translational Research
Volume 155, Issue 5 , Pages 211-216 , May 2010

New type of human blood stem cell: a double-edged sword for the treatment of type 1 diabetes

  • Yong Zhao

      Affiliations

    • Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Ill
    • Corresponding Author InformationReprint requests: Yong Zhao, Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, 1819 W. Polk Street, Chicago, Ill 60612
    • Yong Zhao, MD, PhD is an Assistant Professor of Medicine, Section of Endocrinology, Diabetes & Metabolism, University of Illinois at Chicago.
    • ,
  • Brian Lin

      Affiliations

    • Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Ill
    • ,
  • Michael Dingeldein

      Affiliations

    • Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Ill
    • ,
  • Chengshan Guo

      Affiliations

    • Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Ill
    • ,
  • David Hwang

      Affiliations

    • Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Ill
    • ,
  • Mark J. Holterman

      Affiliations

    • Department of Surgery, University of Illinois at Chicago, Chicago, Ill

Received 1 November 2009 ,Revised 12 January 2010 ,Accepted 13 January 2010.

References 

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  3. Zhao Y, Lin B, Darflinger R, Zhang Y, Holterman MJ, Skidgel RA. Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice. PLoS ONE. 2009;4:e4226
  4. Zhao Y, Huang Z, Qi M, Lazzarini P, Mazzone T. Immune regulation of T lymphocyte by a newly characterized human umbilical cord blood stem cell. Immunol Lett. 2007;108:78–87
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  28. Chao KC, Chao KF, Fu YS, Liu SH. Islet-like clusters derived from mesenchymal stem cells in Wharton's Jelly of the human umbilical cord for transplantation to control type 1 diabetes. PLoS ONE. 2008;3:e1451

PII: S1931-5244(10)00010-1

doi: 10.1016/j.trsl.2010.01.003

Translational Research
Volume 155, Issue 5 , Pages 211-216 , May 2010

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