« Previous
Next »
Translational Research
Volume 155, Issue 5
, Pages 238-246
, May 2010
Serum levels of apelin and ghrelin in patients with acute coronary syndromes and established coronary artery disease—KOZANI STUDY
References
- . Evidence of systemic inflammation and estimation of coronary artery disease risk: a population perspective. Am J Med. 2008;121:S15–S20
- . Adipose inflammation, insulin resistance, and cardiovascular disease. JPEN J Parenter Enteral Nutr. 2008;32:638–644
- Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun. 1998;251:471–476
- . Emerging roles of apelin in biology and medicine. Pharmacol Ther. 2005;107:198–211
- . Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells. Regul Pept. 2005;126:233–240
- Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. FASEB J. 2007;21:1821–1830
- . Visfatin and apelin, new adipokines, and their relation to endothelial function in patients with chronic renal failure. Adv Med Sci. 2008;53:32–36
- Direct effects of apelin on cardiomyocyte contractility and electrophysiology. Biochem Biophys Res Commun. 2007;357:889–895
- Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation. Am J Physiol Heart Circ Physiol. 2009;296:H1329–H1335
- Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest. 2008;118:3343–3354
- Requirement of apelin-apelin receptor system for oxidative stress-linked atherosclerosis. Am J Pathol. 2007;171:1705–1712
- . Reduced apelin levels in stable angina. Intern Med. 2008;47:1951–1955
- . Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect. Curr Drug Discov Technol. 2009;6:34–42
- . Ghrelin and obestatin modulate early atherogenic processes on cells: enhancement of monocyte adhesion and oxidized low-density lipoprotein binding. Metabolism. 2009;58:1572–1580
- Novel markers of carotid atherosclerosis in patients with type 2 diabetes. Exp Clin Endocrin Diab. 2008;35:661–668
- . The new diagnostic criteria for diabetes: the impact on management of diabetes and macrovascular risk factors. Am J Med. 1998;105:15S–19S
- . A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol. 1983;51:606–607
- . The role of apelin in cardiovascular function and heart failure. Eur J Heart Fail. 2008;10:725–732
- Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. FASEB J. 2007;21:1821–1830
- Plasma apelin concentration is depressed following acute myocardial infarction in man. Eur J Heart Fail. 2009;11:551–558
- Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Circulation. 2003;108:1432–1439
- Atherosclerotic plaque stability—what determines the fate of a plaque?. Prog Cardiovasc Dis. 2008;51:183–194
- . Reducing morbidity and mortality in high risk patients with statins. Vasc Health Risk Manag. 2009;5:495–507
- Effects of rosiglitazone and metformin treatment on apelin, visfatin, and ghrelin levels in patients with type 2 diabetes mellitus. Metabolism. 2009;E-pub ahead of print
- . The effects of obesity-related peptides on the vasculature. Curr Vasc Pharmacol. 2006;4:79–85
- Plasma ghrelin levels are associated with coronary microvascular and endothelial dysfunction in peritoneal dialysis patients. Ren Fail. 2009;31:807–813
- Plasma des-acyl ghrelin, but not plasma HMW adiponectin, is a useful cardiometabolic marker for predicting atherosclerosis in elderly hypertensive patients. Atherosclerosis. 2009;204:590–594
- Ghrelin, glucose homeostasis, and carotid intima media thickness in kidney transplantation. Transplantation. 2007;84:1248–1254
- . Ghrelin and cardiovascular health. Curr Opin Pharmacol. 2006;6:142–147
- . Functional and immunocytochemical evidence for a role of ghrelin and des-octanoyl ghrelin in the regulation of vascular tone in man. Cardiovasc Res. 2006;69:227–235
- . [125I-His(9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with athersclerosis. Br J Pharmacol. 2001;134:143–149
- . Pathophysiological levels of the obesity related peptides resistin and ghrelin increase adhesion molecule expression on human vascular endothelial cells. Clin Exp Pharmacol Physiol. 2005;32:839–844
- Ghrelin vaccination decreases plasma MCP-1 level in LDLR(-/-)-mice. Peptides. 2009;30:2292–2300
- Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells. Circulation. 2004;109:2221–2226
- A growth hormone-releasing peptide that binds scavenger receptor CD36 and ghrelin receptor up-regulates sterol transporters and cholesterol efflux in macrophages through a peroxisome proliferator-activated receptor gamma-dependent pathway. Mol Endocrinol. 2006;20:3165–3178
- LDL-cholesterol lowering increases plasma apelin in isolated hypercholesterolemia. Atherosclerosis. 2009;204:222–228
- Short-term therapy with atorvastatin or fenofibrate does not affect plasma ghrelin, resistin or adiponectin levels in type 2 diabetic patients with mixed hyperlipoproteinaemia. Acta Diabetol. 2007;44:65–68
- Intensive lipid-lowering therapy ameliorates novel calcification markers and GSM score in patients with carotid stenosis. Eur J Vasc Endovasc Surg. 2008;35:661–668
Supported by the Alexander S. Onassis Public Benefit Foundation.
PII: S1931-5244(10)00029-0
doi: 10.1016/j.trsl.2010.01.004
© 2010 Mosby, Inc. All rights reserved.
« Previous
Next »
Translational Research
Volume 155, Issue 5
, Pages 238-246
, May 2010
