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The effect of barium chloride on the whole auricle and on strips of ventricle of the turtle heart has been studied. The principal action of the drug was to increase rhythmicity. This effect was more marked when the rate of beating was relatively low, and also when the tissue had been removed from the animal for twenty-four or more hours. Contractility was usually depressed. The influence on excitability, measured by the Q-T of the electrogram, and on muscle fiber conduction was slight.
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Received: April 27, 1945
© 1945 Published by Elsevier Inc.