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Research Article| Volume 30, ISSUE 9, P774-779, September 1945

Diminution of epinephrine sensitivity of the normal human heart through thiouracil

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      References

        • Raab W.
        The Pathogenic Significance of Adrenalin and Related Substances in the Heart Muscle.
        Exper. Med. & Surg. 1943; 1: 188
        • Raab W.
        Cardiotoxic Substances in the Blood and Heart Muscle in Uremia (Their Nature and Action).
        J. Lab. & Clin. Med. 1944; 29: 715
        • Raab W.
        Sudden Death of a Young Athlete With an Excessive Concentration of Epinephrine-Like Substances in the Heart Muscle.
        Arch. Path. 1943; 36: 388
        • Raab W.
        Sudden death With an Excessive Myocardial Concentration of Epinephrine-Like Substances in a Case of Obesity and Cystic Thyroid Disease.
        Arch. Path. 1944; 38: 110
        • Raab W.
        Epinephrine Tolerance of the Heart Altered by Thyroxine and Thiouracil.
        J. Pharmacol. & Exper. Therap. 1945; 82: 330
        • Raab W.
        Thiouracil for Angina Pectoris. Rationale and Results.
        J. A. M. A. 1945; 128: 249
        • Raab W.
        • Soule Jr., A.B.
        Rationale and Results of Roentgen Treatment of the Adrenal Glands in Angina Pectoris.
        Am. J. Roentgenol. 1944; 51: 364
        • Lütolf W.
        Untersuchungen über die Sensibilisierung von Adrenalin durch Thyroxin am überlebenden Säugetierherzen.
        Ztschr. f. Biol. 1930; 90: 334
        • Sadae O.
        On the Sensitizing Action of Thyroid Extract for Adrenalin.
        Japan. Med. World. 1932; 2: 157
        • Steppuhn O.
        • Naumova N.
        • Ugarova N.
        Chemical and Pharmacodynamic Characteristics of the Heart in Hyperthyroidism.
        Klin. med. 1935; 13 (Russian): 1265
        • Sawyer M.E.A.
        • Brown M.G.
        The Effect of Thyroidectomy and Thyroxine on the Response of the Denervated Heart to Injected and Secreted Adrenine.
        Am. J. Physiol. 1935; 110: 620
        • Wise B.
        • Hoff H.E.
        The Effect of Autonomic Hormones on the Thyrotoxic Heart.
        J. Pharmacol. & Exper. Therap. 1938; 64: 217
        • Aumann K.W.
        • Youmans W.B.
        Differential Sensitization of Adrenergic Neuro-Effector System by the Thyroid Hormone.
        Am. J. Physiol. 1940; 131: 394
        • Gross H.
        • Greenberg S.S.
        The Effect of Thyroid Extract, Adrenalin and a Combination of These on the Hearts of Intact and Thyroidectomized Rats.
        Am. Heart J. 1944; 27: 186
        • Schermann S.J.
        Die Reaktion des isolierten Herzens eines thyreoidektomierten Tieres auf Adrenalin.
        Arch. f. exper. Path. u. Pharmakol. 1927; 126: 10
        • Shambaugh Ph.
        • Cutler E.C.
        Total Thyroidectomy in Angina Pectoris.
        Am. Heart J. 1934; 10: 221
        • Eppinger E.C.
        • Levine S.A.
        Effect of Total Thyroidectomy on the Response to Adrenalin.
        in: Proc. Soc. Exper. Biol. & Med. 31. 1935: 485
        • Lev M.W.
        • Hamburger W.W.
        Studies in Thyroid Heart Disease. II. Angina Pectoris and Hyperthyroidism.
        Am. Heart J. 1932; 8: 109
        • Blumgart H.L.
        • Levine S.A.
        • Berlin D.D.
        The Therapeutic Effect of Thyroidectomy on Patients Without Clinical or Pathological Evidence of Thyroid Toxicity.
        Arch. Int. Med. 1933; 51: 866
        • Astwood E.B.
        Treatment of Hyperthyroidism With Thiourea and Thiouracil.
        J. A. M. A. 1943; 122: 78
        • Astwood E.B.
        Thiouracil Treatment in Hyperthyroidism.
        J. Clin. Endocrinol. 1944; 4: 229
        • Riseman J.E.F.
        • Gilligan D.R.
        • Blumgart H.L.
        Treatment of Congestive Heart Failure and Angina Pectoris by Total Ablation of the Normal Thyroid Gland. XVI. The Sensitivity of Man to Epinephrine Injected Intravenously Before and After Total Thyroidectomy.
        Arch. Int. Med. 1935; 56: 39
        • Leblond C.P.
        • Hoff H.E.
        Effect of Sulfonamides and Thiourea Derivatives on Heart Rate and Organ Morphology.
        Endocrinology. 1944; 35: 229
        • Leblond C.P.
        • Hoff H.E.
        Comparison of Cardiac and Metabolic Actions of Thyroxine, Thyroxine Derivatives and Dinitrophenol in Thyroidectomized Animals.
        Am. J. Physiol. 1944; 141: 32
        • DiPalma J.R.
        • Dreyer N.B.
        Failure of Thiourea to Alter the Autonomic Responses of Intact Animals.
        Endocrinology. 1945; 36: 236