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Abstract
A combination of streptomycin and glucuronic acid was given orally to a group of six
patients. This group of patients was followed with quantitative stool cultures and
quantitative urinary indican determinations at daily intervals.
In five of the six patients it was found that the excretion of indican did not diminish
when organisms were eliminated from the stools.
It is apparent that the urinary indican excretion is not dependent on Esch. coli activity in the bowel. This necessitates some modification in the concept of “intestinal
putrefaction.”
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References
Mast, G. M., and Harrison, P.: Unpublished data.
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Donaldson, R. C.: Personal communication.
- The Effects of Uronic Acids, Pectins and Pectinates on the Enteric Flora, Alone and in Combination With Antibiotics. I. In Vitro Studies.Am. J. Surg. 1949; 78: 881
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Article info
Publication history
Received:
April 26,
1950
Footnotes
☆Studies, observations and reports from the Research Laboratory, St. John's Hospital, Springfield, Mo., and the Department of Dermatology of the Barnard Free Skin and Cancer Hospital and Washington University School of Medicine, St. Louis, Mo., service of Dr. Richard S. Weiss.
☆☆This study was accomplished under a research grant from the Commercial Solvents Corporation, New York, N. Y.
Identification
Copyright
© 1950 Published by Elsevier Inc.
