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Abstract
By means of the study of the survival of transfused erythrocytes an intrinsic erythrocyte
abnormality was demonstrated in members of two families with atypical chronic familial
hemolytic anemia.
The pattern of elimination of the patients' erythrocytes transfused into normal recipients
was similar to that, in sickle cell anemia and congenital hemolytic icterus.
Normal erythrocytes transfused into these patients had normal survival except following
a fulminating crisis in one child when the survival method enabled us to demonstrate
a superimposed acquired extracorpuscular hemolytic disturbance.
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References
- The Life Span of the Sickle Cell and the Pathogenesis of Sickle Cell Anemia.J. Lab. & Clin. Med. 1948; 33: 975
- Survival of Normal Erythrocytes After Transfusion to Patients With Familial Hemolytic Anemia.Lancet. 1943; 244: 550
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- Survival of Transfused Erythrocytes From a Donor With Nocturnal Hemoglobinuria.Lancet. 1949; 141: 390
- The Life Span of the Megalocyte and the Hemolytic Syndrome of Pernicious Anemia.J. Lab. & Clin. Med. 1948; 33: 1068
- Hereditary Nonspherocytic Hemolytic Anemia.Blood. 1950; 5: 233
- Familial Non-spherocytic Hemolytic Anemia.Blood. 1950; 5: 811
Article info
Publication history
Received:
May 25,
1950
With the Technical Assistance of Linda Hoogana, M.S.Identification
Copyright
© 1950 Published by Elsevier Inc.
