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Abstract
An antihistamine was used in prophylactic dosage in 352 male recruits throughout their
training period. A group comparable in size and stages of training was treated with
placebos, and a third similar group was given no treatment. A high incidence of acute
respiratory diseases occurred in the population during the study between February
and April, 1950, the majority of which were clinically classifiable as the common
cold. An epidemic of influenza due to influenza virus, type A prime, complicated the
study and it was not possible to effect a completely satisfactory clinical separation
of all cases of influenza from other types of respiratory disease. No evidence was
found that the antihistamine prevented these diseases or effected any important alteration
in their symptomatology.
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Article info
Publication history
Received:
June 19,
1950
Footnotes
☆The opinions expressed herein are those of the authors and cannot be construed as reflecting the views of the Navy Department or of the Naval Service at large.
☆☆The use of commercially available products or preparations in connection with this project cannot be construed as indicating endorsement or approval of such products by the Naval Service or by the authors, nor as preference for one brand of antihistamine to the exclusion of other similar products on the market.
Identification
Copyright
© 1950 Published by Elsevier Inc.
