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Research Article| Volume 36, ISSUE 4, P584-590, October 1950

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The prophylaxis and treatment of acute respiratory diseases with antihistaminic drugs

IV. The prophylaxis and treatment of “colds” in volunteers
  • The Personnel of United States Naval Medical Research Unit No. 4
    Footnotes
    Affiliations
    From Research Project NM 005 051.11 Research Division, Bureau of Medicine and Surgery, Navy Department, Washington, D. C., USA
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  • Author Footnotes
    ∗ United States Naval Training Center, Great Lakes, Ill. Participating in this study were: CDR J. R. Seal, MC USN, Director; LT C. E. Curtis, MSC USN, Biomtrician; LT L. E. Anthony, MC USN, Clinical Coordinator; WO R. T. Goerner, Jr., HC USN, Field Laboratory; LT L. A. Ruffer, NC USN; Lt L. Howerton, NC USNR; Miss R. M. Schlemmer; and other civilian and enlisted personnel. Consultants were: Thomas G. Ward, M.D., Johns Hopkins University, Baltimore, Md.; Clayton G. Loosli, M.D., and William E. Lester, M.D., the University of Chicago School of Medicine, Chicago, Ill.
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      Abstract

      Several antihistaminic drugs were issued to volunteers among families of officers and senior petty officers in both prophylactic and therapeutic dosage schedules and compared with the use of placebos. Too few reported adequate usage of the drugs in the prophylactic schedule to allow any critical evaluation of results. Those reporting the therapeutic usage had equally beneficial results from placebos and antihistaminic drugs, presumably because of psychological effects.
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      References

        • United States Naval Medical Research Unit No. 4
        The Prophylaxis and Treatment of Acute Respiratory Disease With Antihistaminic Drugs. I. Prophylactic Treatment in Navy Male Recruits.
        J. Lab. & Clin. Med. 1950; 36: 555
        • United States Naval Medical Research Unit No. 4
        The Prophylaxis and Treatment of Acute Respiratory Diseases With Antihistaminic Drugs. II. Prophylactic Treatment With Therapeutic Dosage in Navy Male Recruits.
        J. Lab. & Clin. Med. 1950; 36: 570
        • United States Naval Medical Research Unit No. 4
        The Prophylaxis and Treatment of Acute Respiratory Diseases With Antihistaminic Drugs. III. Treatment of Minor Acute Respiratory Infection in Navy Wave Recruits.
        J. Lab. & Clin. Med. 1950; 36: 576
        • Brewster J.M.
        Antishistaminic Drugs in the Therapy of the Common Cold.
        U. S. Nav. M. Bull. 1949; 49: 1-11