Research Article| Volume 36, ISSUE 4, P652-654, October 1950

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A further report on the comparison of the one-stage and bedside methods for determining prothrombin

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      Paired prothrombin determinations have been done by the bedside and one-stage methods using the type of stable thromboplastin available for the previous work and the more recent commercially available Solu-Plastin.
      A correlation coefficient of 0.870 was found for the older type of thromboplastin, thus confirming the report in a previous communication.1
      The newer type of thromboplastin, Solu-Plastin, did not give a direct correlation between the values obtained by the bedside and one-stage methods.
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        • Lewis D.W.
        • Munro F.L.
        • Munro M.P.
        Prothrombin Determinations in Dicumarolized Patients; A Comparison of the One-Stage and Bedside Methods.
        J. Lab. & Clin. Med. 1950; 35: 16-23
        • Ziffren S.E.
        • Owen C.A.
        • Hoffman G.R.
        • Smith H.P.
        A Simple Bedside Test for Control of Vitamin K Therapy.
        Am. J. Clin. Path., Tech. Supp. 1940; 4: 13-16
        • Quick A.J.
        The Prothrombin in Hemophilia and in Obstructive Jaundice.
        J. Biol. Chem. 1935; 109: lxxiii, lxxiv
      1. Blanchard, E. W., and Gerber, C. F.: Personal communication.

        • Gerber C.F.
        • Blanchard E.W.
        Factors in the Lability of Thromboplastin Solutions.
        in: ed. 4. Federation Proc. 9. 1950: 47
        • Snedecor G.W.
        Statistical Methods Applied to Experiments in Agriculture and Biology.
        in: ed. 4. The Collegiate Press, Inc, Ames, Iowa1946: 138