Research Article| Volume 36, ISSUE 4, P660-666, October 1950

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The production of chronic systemic hypertension in the rat with a small adjustable renal artery clamp

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        • Grollman A.
        • Williams Jr., J.R.
        Experimental Chronic Hypertension in Rat.
        Am. J. M. Sc. 1942; 204: 73
        • Abrams M.
        • Sobin S.
        Latex Rubber Capsule for Producing Hypertension in Rats by Perinephritis.
        in: ed. 12. Proc. Soc. Exper. Biol. & Med. 64. 1947: 412
        • Page E.W.
        • Patton H.S.
        • Ogden E.
        Effect of Pregnancy on Experimental Hypertension, With Observations on Effects of Deciduomas.
        Am. J. Obst. & Gynec. 1941; 41: 53
        • Remington J.W.
        • Cartland G.F.
        • Drill V.A.
        • Swingle W.W.
        Purification and Bioassay of Tissue Extracts Capable of Lowering the Blood Pressure of Hypertensive Rats.
        Am. J. Physiol. 1944; 140: 627
        • Chanutin A.
        • Ferris Jr., E.B.
        Experimental Renal Insufficiency Produced by Partial Nephrectomy; Control Diet.
        Arch. Int. Med. 1932; 49: 767
        • Kempf G.F.
        • Page I.H.
        Production of Experimental Hypertension and Indirect Determination of Systolic Arterial Pressure in Rats.
        J. Lab. & Clin. Med. 1942; 27: 1192
        • Wilson C.
        • Byrom F.B.
        Vicious Circle in Chronic Bright's Disease. Experimental Evidence From Hypertensive Rat.
        Quart. J. Med. 1941; 10: 65
        • Grollman A.
        A Simplified Procedure for Inducing Chronic Renal Hypertension in the Mammal.
        in: ed. 12. Proc. Soc. Exper. Biol. & Med. 57. 1944: 102
        • Goldblatt H.
        • Lynch J.
        • Hanzal R.F.
        • Summerville W.W.
        Studies on Experimental Hypertension. I. The Production of Persistent Elevation of Systolic Blood Pressure by Means of Renal Ischemia.
        J. Exper. Med. 1934; 59: 347
        • Munnell E.R.
        • Gregg D.E.
        A Small Adjustable Renal Artery Clamp for Production of Chronic Hypertension in the Rat.
        in: ed. 12. Proc. Soc. Exper. Biol. & Med. 73. 1950: 645
      1. Ablondi, F.: Personal communication, 1948.

        • Page I.H.
        Method for Producing Persistent Hypertension by Cellophane.
        Science. 1939; 89: 273
        • Kersten H.
        • Brosene Jr., W.G.
        • Ablondi F.
        • SubbaRow Y.
        A New Method for the Indirect Measurement of Blood Pressure in the Rat.
        J. Lab. & Clin. Med. 1947; 32: 1090
        • Hawk P.B.
        • Oser B.L.
        • Summerson W.H.
        Practical Physiological Chemistry.
        in: ed. 12. The Blakiston Company, Philadelphia1947: 495