Research Article| Volume 36, ISSUE 1, P82-86, July 1950

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Activation and action of the fibrinolytic human blood plasma fractions

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      The optimum pH for fibrinolytic activity of Fraction III-3 of human blood is between 6.8 and 7.2.
      The greater the concentration of lysin, the more rapid the lysis of a standard human clot would occur; however, the greatest concentration of lysin used did not prevent the clot from forming.
      Filter paper shows lysokinase activity when tested on the prolysin of human plasma Fraction I but not on the whole plasma clot.
      Human albumin has some antilysokinase activity.
      Injections of human plasma Fraction III-3 into dogs lengthens the prothrombin time and the clotting time, and increases antithrombin activity of the dog blood.
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