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Abstract
The optimum pH for fibrinolytic activity of Fraction III-3 of human blood is between
6.8 and 7.2.
The greater the concentration of lysin, the more rapid the lysis of a standard human
clot would occur; however, the greatest concentration of lysin used did not prevent
the clot from forming.
Filter paper shows lysokinase activity when tested on the prolysin of human plasma
Fraction I but not on the whole plasma clot.
Human albumin has some antilysokinase activity.
Injections of human plasma Fraction III-3 into dogs lengthens the prothrombin time
and the clotting time, and increases antithrombin activity of the dog blood.
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References
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Article info
Publication history
Received:
March 24,
1950
Footnotes
☆This study was aided in part by a grant from the Abbott Laboratories, North Chicago, Ill.
Identification
Copyright
© 1950 Published by Elsevier Inc.
