This paper is only available as a PDF. To read, Please Download here.
Abstract
The results of a series of 200 pregnancy tests using simultaneously a rabbit and two
male frogs for each specimen are reported. During the summer months, frogs rendered
20 per cent false negative results.
∗Similar observations were reported since this article was submitted: Samson, M.: Seasonal
Variation in Sensitivity of Rana pipiens to Chorionic Gonadotropin, Science 111:231, 1950.
An attempt is made to explain this phenomenon. The total number of false negative
results in the series was 10 per cent. A positive result obtained with male frogs
is reliable. A negative result cannot be relied upon and has to be confirmed or repudiated
by other pregnancy tests.To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Translational ResearchAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Pregnancy Test Using Male Toad.J. Clin. Endocrinol. 1947; 7: 653
- Pregnancy Test Using Male Batrachia.J. A. M. A. 1948; 138: 121
- Male Frog, Rana pipiens, as New Test Animal for Early Pregnancy.Science. 1948; 107: 198
- Use of the Male North American Frog, Rana pipiens, in the Diagnosis of Pregnancy.Endocrinology. 1948; 42: 237
- Pregnancy Tests.New England J. Med. 1948; 239: 333
- Pregnancy Tests.New England J. Med. 1948; 239: 369
- The Reliability of the Male North American Frog (Rana pipiens) in the Diagnosis of Pregnancy.New England J. Med. 1949; 241: 12
- Quantitative Bio-assay of Chorionic Gonadotrophin With the Male Frog.Endocrinology. 1949; 44: 542
- Use of English Male Toads in Pregnancy Test.Lancet. 1949; 2: 9
- Use of the Male Frog (Rana pipiens) in a Biological Pregnancy Test.J. Obst. & Gynec. 1950; 59: 350
- The Reaction of Male Frogs to Epinephrine.Endrocrinology. 1949; 44: 384
Article info
Publication history
Received:
February 20,
1950
Identification
Copyright
© 1950 Published by Elsevier Inc.
