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The results of a series of 200 pregnancy tests using simultaneously a rabbit and two male frogs for each specimen are reported. During the summer months, frogs rendered 20 per cent false negative results.
∗Similar observations were reported since this article was submitted: Samson, M.: Seasonal Variation in Sensitivity of Rana pipiens to Chorionic Gonadotropin, Science 111:231, 1950.An attempt is made to explain this phenomenon. The total number of false negative results in the series was 10 per cent. A positive result obtained with male frogs is reliable. A negative result cannot be relied upon and has to be confirmed or repudiated by other pregnancy tests.
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Received: February 20, 1950
© 1950 Published by Elsevier Inc.