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Abstract
Studies on the rate of decline of the blood sugar level calculated for the 30 to 60
minute period of the modified G.I.T.T. were carried out on ten nondiabetic individuals
using the following insulin dosages: (1) 0.01 unit per kilogram, (2) 0.02 unit per
kilogram, (3) 0.05 unit per kilogram, (4) 0.10 unit per kilogram, (5) 0.20 unit per
kilogram, (6) 0.30 unit per kilogram. It was found that the mean rate of decline was
proportional to the insulin dosage up to 0.05 unit per kilogram. Further increase
in insulin dosage up to 0.30 unit per kilogram caused no further acceleration of the
rate of decline. From these observations it is concluded that 0.1 unit per kilogram
is probably the most satisfactory dosage for use in the modified G.I.T.T. in the estimation
of insulin sensitivity.
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Article info
Publication history
Received:
October 13,
1952
Identification
Copyright
© 1953 Published by Elsevier Inc.
