Research Article| Volume 41, ISSUE 5, P782-788, May 1953

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Some observations on the assay of staphylococcal enterotoxin by the monkey-feeding test

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      A wide variation in susceptibility was found in approximately 1,000 Macaca mulatta injected intragastrically with staphylococcal enterotoxin. The relative susceptibility of animals can be predicted to some degree on the basis of past response to enterotoxin.
      Graded dosage-response curves are not very satisfactory unless new animals are used.
      Unprovoked emesis has been observed on rare occasions.
      False positive vomiting reactions due to a dialyzable agent have been encountered in experimental preparations. These reactions were promptly detected by the use of proper controls.
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