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Research Article| Volume 41, ISSUE 5, P802-811, May 1953

Studies on primary amines

I. Methods
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      Abstract

      Methods are described for isolation of primary amines on paper chromatograms, their partial identification, and methods of quantitative determination of known primary amines.
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      References

        • Stock C.C.
        • Schroeder H.A.
        Pressor Substances in Arterial Blood: Activity and Amine Content of Crude Extracts of Blood.
        Am. J. Physiol. 1950; 160: 409-420
        • Bing R.J.
        • Zucker M.B.
        Formation of Pressor Amines in the Kidney.
        in: Proc. Soc. Exper. Biol. & Med. 46. 1941: 343-347
        • Braun-Menendez E.
        • Fasciolo J.C.
        • Leloir S.F.
        • Muñoz J.M.
        The Substance Causing Renal Hypertension.
        J. Physiol. 1940; 98: 283-298
        • Shipley R.E.
        The Presence in Blood of a Principle Which Elicits Sustained Pressor Response in Nephrectomized Animals.
        Am. J. Physiol. 1947; 149: 708
        • von Euler U.S.
        • Schmiterlow C.G.
        Sympathomimetic Activity in Extracts of Normal Human and Bovine Blood.
        Acta Physiol. Scandinav. 1947; 13: 1-8
        • von Euler U.S.
        • Sjöstrand T.
        Pressor Activity in Blood and Plasma From Normal Subjects and Patients With Essential Hypertension.
        Acta med. Scandinav. 1944; 119: 1-17
        • Kreutzfeldt H.
        Attempts to Demonstrate the Presence of Pressor Substances in the Blood of Patients With Renal Hypertension.
        Acta med. Scandinav. 1946; 125: 171-181
        • Lockett M.F.
        The Pressor Bases of Normal Urine.
        J. Physiol. 1944; 103: 68-92
        • Lockett M.F.
        The Isolation and Identification of a Pressor Base from Normal Urine.
        J. Physiol. 1944; 103: 185-232
        • von Euler U.S.
        • Sjöstrand T.
        Pressor Activity in Urine in Hypertension.
        Acta med. Scandinav. 1945; 120: 276-287
        • von Euler U.S.
        • Sjöstrand T.
        Pressor Substances in Urine and Plasma From Normal and Hypertensive Subjects.
        Nature. 1943; 151: 168
        • Page I.H.
        Vascular Action of Fresh Urine and Extracts Thereof.
        in: Proc. Soc. Exper. Biol. & Med. 32. 1934–1935: 302-304
        • Davies D.F.
        • Miller H.
        • Schroeder H.A.
        Association Between Primary Amines and Pressor Substances in Urine.
        Am. J. Med. 1951; 10: 240
        • Handler P.
        • Bernheim F.
        The Biochemical Basis for Renal Hypertensoin.
        J. Gerontol. 1951; 6: 98
        • Harrison T.R.
        • Williams Jr., J.R.
        • Grollman A.
        Pressor Properties of Extracts From Normal and Abnormal Kidneys.
        Tr. A. Am. Physicians. 1940; 55: 289
        • Victor J.
        • Steiner A.
        • Weeks D.M.
        A Pressor Substance Produced by Anaerobic Autolysis of Renal Cortex.
        in: Proc. Soc. Exper. Biol. & Med. 42. 1939: 767
        • Kohlstaedt K.G.
        • Page I.H.
        The Liberation of Renin by Perfusion of Kidneys Following Reduction of Pulse Pressure.
        J. Exper. Med. 1940; 72: 201
        • Rapport M.M.
        Serum Vasoconstrictor (Serotonin). V. The Presence of Creatinine in the Complex. A Proposed Structure of the Vasoconstrictor Principle.
        J. Biol. Chem. 1949; 180: 961-969
        • Holtz P.
        Über Die Entstehung von Histamin und Tyramin Im Organismus.
        Klin. Wchnschr. 1937; 162: 1561-1567
        • Holtz P.
        • Heise R.
        Fermentativer Abbau von 1-Dioxyphenylalanin (Dopa) durch Niere.
        Arch. f. Exper. Path. und Pharmakol. 1939; 191: 87-118
        • Blaschko H.
        Activity of 1-(-)-Dopa Decarboxylase.
        J. Physiol. 1942; 101: 337-349
        • Olsen N.S.
        • Schroeder H.A.
        Pressor Substances in Arterial Hypertension III. Chemical Studies on Pherentasin.
        J. Exper. Med. 1950; 92: 561-570
        • Davies D.F.
        • Olsen N.S.
        • Schroeder H.A.
        Pressor Substances in Arterial Hypertension IV. Quantitative and Qualitative Studies of Pherentasin.
        Circulation. 1952; 5: 380-389
        • Guggenheim M.
        Die biogenen Amine.
        S. Karger, New York1951
        • Richter D.
        Elimination of Amines in Man.
        Biochem. J. 1938; 32: 1763-1769
        • Urbach K.F.
        Nature and Probable Origin of Conjugated Histamine Excreted After Ingestion of Histamine.
        in: Proc. Soc. Exper. Biol. & Med. 70. 1949: 146
        • Brodie B.B.
        • Udenfriend S.
        The Estimation of Basic Organic Compounds and a Technique for the Appraisal of Specificity. Application to the Cinchona Alkaloids.
        J. Biol. Chem. 1945; 158: 705-714
        • Elias K.
        • Elias H.
        Some Studies on Basic Amines in the Blood Under Physiologic and Pathologic Conditions.
        Exper. Med. & Surg. 1950; 8: 89-101
        • Elson L.A.
        • Morgan W.T.J.
        A Colorimetric Method for the Determination of Glucosamine and Chondrosamine.
        Biochem. J. 1933; 27: 1824-1828
        • West L.
        • Clarke D.H.
        The Concentration of Glucosamine in Normal and Pathological Sera.
        J. Clin. Investigation. 1938; 17: 173-178
        • Beyer K.A.
        • Shapiro S.H.
        The Execretion of Conjugated Epinephrine Related Compounds.
        Am. J. Physiol. 1945; 144: 321-330
        • Raab W.
        The Presence and Chemical Determination of Adreno-Cortical (‘AC’) Compounds in the Blood.
        Endocrinol. 1941; 28: 325-336
        • Raab W.
        Distribution of Adreno-Cortical (‘AC’) Hormones in Tissues of the Rat Under Normal and Experimental Conditions.
        Endocrinol. 1941; 29: 126-136
        • von Euler U.S.
        • Hamberg U.
        • Hellner S.
        β-(3:4-Dihydroxyphenyl) ethylamine (hydroxytyramine) in Normal Human Urine.
        Biochem. J. 1951; 49: 655-658
        • Williams R.J.
        • Kirby H.
        Paper Chromatography Using Capillary Ascent.
        Science. 1948; 107: 481
        • Bremner I.M.
        • Kenten R.H.
        Paper Chromatography of Amines.
        Biochem. J. 1951; 49: 651-655
        • Fitzpatrick W.H.
        Spectrophotometric Determination of Amino Acids by the Ninhydrin Reaction.
        Science. 1949; 109: 469
      1. Perry, H. M., and Davies, D. F.: To be published.

        • Consden R.
        • Gordon A.H.
        • Martin A.J.P.
        Qualitative Analysis of Proteins; A Partition Chromatographic Method Using Paper.
        Biochem. J. 1944; 38: 224
        • Moore S.
        • Stein W.H.
        Photometric Ninhydrin Method for Use in the Chromatography of Amino Acids.
        J. Biol. Chem. 1948; 176: 367-388