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A simple, reproducible method for the determination of serum alkaline phosphatase activity has been described. The measurement of enzyme activity may be carried out with as little as 0.01 ml. of serum. Normal values of serum alkaline phosphatase activity varied from 0.8 to 4.5 micromol units, with an average value of 2.3 ± 0.9 units.
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Received: January 23, 1953
☆Aided by a grant from the National Institutes of Health, U. S. Public Health Service.
© 1953 Published by Elsevier Inc.