Clinical and experimental| Volume 44, ISSUE 2, P177-184, August 1954

The hemolytic effect of primaquine, III. A study of primaquine-sensitive erythrocytes

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      The erythrocytes of primaquine-sensitive and nonsensitive individuals not receiving primaquine have been compared in the following respects: (a) morphology; (b) antigenic characteristics; (c) sensitivity to acid hemolysis; (d) hemoglobin type; (e) mechanical, osmotic, and chemical fragility; (f) the fragility to the in vitro hemolytic action of primaquine, pamaquine, 6-methoxy-quinoline, quinoline, and aniline; and (g) susceptibility to the accelerating effect of naphthalene and primaquine on taurocholate or saponin hemolysis.
      The morphology, Coombs' tests, hemoglobin type, and osmotic and mechanical fragility of the erythrocytes have also been studied during the various phases of the hemolytic reaction.
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