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Abstract
The erythrocytes of primaquine-sensitive and nonsensitive individuals not receiving
primaquine have been compared in the following respects: (a) morphology; (b) antigenic
characteristics; (c) sensitivity to acid hemolysis; (d) hemoglobin type; (e) mechanical,
osmotic, and chemical fragility; (f) the fragility to the in vitro hemolytic action
of primaquine, pamaquine, 6-methoxy-quinoline, quinoline, and aniline; and (g) susceptibility
to the accelerating effect of naphthalene and primaquine on taurocholate or saponin
hemolysis.
The morphology, Coombs' tests, hemoglobin type, and osmotic and mechanical fragility
of the erythrocytes have also been studied during the various phases of the hemolytic
reaction.
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Article info
Publication history
Received:
April 23,
1954
Footnotes
☆This investigation was carried out under contract number DA-49-007-MD-20 between the Office of the Surgeon General, United States Army, and the Department of Medicine of the University of Chicago.
☆☆This work was further aided by the participation of Army Medical Officers assigned to the project by the Surgeon General of the United States Army.
★The investigation reported in this paper would not have been possible except for the cooperation of the inmates and the administrative staff of Stateville Penitentiary.
Identification
Copyright
© 1954 Published by Elsevier Inc.
