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Abstract
Antistreptolysin “O” and gamma globulin levels decrease most rapidly in patients with
rheumatic fever who receive ACTH. Although the difference between the cortisone-treated
and aspirin-treated groups was not statistically significant, cortisone appeared to
decrease the elevated antistreptolysin and gamma globulin concentrations more rapidly
than aspirin.
Following the cessation of treatment in all three groups, there were slight increases
in the average gamma globulin concentration without similar increases in the average
antistreptolysin “O” titer.
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References
- Thomas L. Rheumatic Fever, A Symposium. University of Minnesota Press, Minneapolis1952: 136
- Quantitative Antistreptokinase Studies in Patients Infected With Group A Hemolytic Streptococci; Comparison With Serum Antistreptolysin and Gamma Globulin Levels With Special Reference to the Occur rence of Rheumatic Fever.J. Clin. Invest. 1948; 27: 425-434
- Mote J.R. Proceedings of the First Clinical ACTH Conference. The Blakiston Co, Philadelphia1950: 405
- Reappearance of Abnormal Laboratory Findings in Rheumatic Patients Following Withdrawal of ACTH or Cortisone.Am. J. M. Sc. 1951; 222 (With Special Reference to C-Reactive Protein): 516-522
- Observations on the Physiologic Effects of Cortisone and ACTH in Man.Arch. Int. Med. 1950; 85: 199-258
- Comparative Effects of Aspirin, ACTH and Cortisone on the Acute Course of Rheumatic Fever in Young Male Adults.Am. J. Med. 1954; 16: 168-180
- Varying hemolytic and Constant Combining Capacity of Streptolysins; Influence on Testing for Antistreptolysins.J. Exper. Med. 1933; 58: 277-287
- Application of Turbidimetric Methods for Estimation of Gamma Globulin and Total Lipid to the Study of Patients With Liver Disease.Gastroenterology. 1948; 11: 499-507
- The Effect of Cortisone and Adrenocorticotrophic Hormone on the Concentration of Circulating Antibody.J. Exper. Med. 1951; 93: 37-48
Article info
Publication history
Received:
May 8,
1954
Footnotes
☆This investigation was conducted under the sponsorship of the Commission on Acute Respiratory Diseases and the Commission on Streptococcal Diseases, Armed Forces Epidemiological Board, and was supported by the Offices of the Surgeons General, Departments of the Army and Air Force, Washington, D. C.
Identification
Copyright
© 1954 Published by Elsevier Inc.
