This paper is only available as a PDF. To read, Please Download here.
Abstract
Magnesium28 was administered to young male albino rats to determine the location of the major
gastrointestinal sites of magnesium absorption and excretion. The results indicate
that magnesium is absorbed throughout the intestinal tract, that in all probability
more is absorbed in the ileum than in the jejunum, and that over 70 per cent of the
total absorption of magnesium occurs in the colon. The pattern of the intestinal excretion
of endogenous magnesium appears to be the reverse of absorption, with most of the
loss occurring in the proximal gut.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Translational ResearchAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Metabolism of Magnesium in the Normal Rat.J. Lab. & Clin. Med. 1964; 63: 80
- Statistical Methods Applied to Experiments in Agriculture and Biology.ed. 5. Iowa State College Press, Ames, Iowa1956
- In Vitro Studies on the Transport of Magnesium Across the Intestinal Wall of the Rat.J. Physiol. 1962; 106: 417
- Absorption of Magnesium in the Large Intestine of the Calf.Nature. 1959; 184: 821
- The Effects of Excessive Intake of Magnesium by the Rat, Especially Concerning the Factors Relating to the Production of Renal Calculi.J. Hygiene. 1932; 32: 156
- Urinary and Fecal Excretion of Orally Administered Mg28.in: ed. 5. Proc. Soc. Exper. Biol. & Med. 98. 1958: 29
- Gastrointestinal Absorption of Mg28 in Rabbits.in: ed. 5. Proc. Soc. Exper. Biol. & Med. 100. 1959: 293
- Serum Magnesium After Oral Administration of Magnesium Salts.Acta pharmacol. et toxicol. 1952; 8: 374
- Gastrointestinal Absorption and Excretion of Mg28 in Man.Metabolism. 1960; 9: 646
- Untersuchenigen Ueber die Magnesiumausscheidung bei Hunden: Ein Beitrag zur Physiologie Des Colons. III.Skandinav. Arch. Physiol. 1936; 73: 75
- Magnesium Poisoning Following an Enema of Epsom Salt Solution.J. A. M. A. 1943; 123: 1028
- Fatal Magnesium Poisoning Following Magnesium Sulfate, Glycerin, and Water Enema in Primary Megacolon.Cleveland Clin. Quart. 1949; 16: 162
- Magnesium Intoxication: Absorption From the Intact Gastrointestinal Tract.Arch. Neurol. & Psychiat. 1950; 63: 749
- Influence of Sodium on the Transport of Magnesium Across the Intestinal Wall of the Rat in Vitro.Nature. 1961; 189: 840
- Blood and Other Body Fluids.Federation of American Societies for Experimental Biology, Washington, D. C1961
- Mg28 Tracer Studies of Magnesium Metabolism in Animals and Human Beings.in: Second United Nations International Conference on the Peaceful Uses of Atomic Energy. ed. 5. Isotopes in Biochemistry and Physiology. vol. 24. United Nations, Geneva1958: 148 (Part 1)
- The Composition of Intestinal Secretion.J. Biol. Chem. 1935; 108: 113
Chutkow, J. G.: Unpublished data.
- A Multiple Comparison Procedure for Comparing Several Treatments With a Control.J. Am. Stat. Assn. 1955; 50: 1096
Article info
Publication history
Accepted:
September 10,
1963
Received:
August 6,
1963
Footnotes
☆The Dunnett t test analysis digital computer program was designed by members of the Biological Sciences Computation Center, University of Chicago, supported by United States Public Health Service Grant No. 1-PO7-FR00013-01.
Identification
Copyright
© 1964 Published by Elsevier Inc.