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Abstract
Heparizined steer blood was sheared in a capillary flow field. By analyzing the amount
of hemoglobin in the plasma before and after shearing, the extent of mechanically
induced hemolysis was determined. Among the parameters which were varied were tube
geometry (lengths, 10 to 40 cm.; diameters, 0.01 to 0.04 inch), wall shear stress
(to 8,000 dynes per square centimeter), hematocrit (0.20 to 0.43), and capillary material.
Several aspects of the experimental results indicated that hemolysis occurs because
of interactions of uncertain character between the red cells and the wall and is related
to cell velocities near the wall. Of particular interest was the varied influence
of different tube material and/or roughness.
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References
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Article info
Publication history
Accepted:
June 10,
1970
Received:
November 6,
1969
Footnotes
☆This study was supported by the Bay Area Heart Research Committee.
Identification
Copyright
© 1970 Published by Elsevier Inc.
