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Abstract
A patient with a severe and prolonged leukemoid reaction secondary to carcinoma of
the lung was found to have a striking increase in plasma vitamin B12-binding protein. This protein had all 7 properties that characterize transcobalamin
I (TC I), a normal constituent of plasma which is much increased in chronic myelogenous
leukemia, This observation must be considered in the use of B12-binding patterns in differential diagnosis.
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References
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Article info
Publication history
Accepted:
March 30,
1971
Received:
January 12,
1971
Footnotes
☆Supported in part by National Institute of Health Grant AMO2808.
Identification
Copyright
© 1971 Published by Elsevier Inc.
