It’s not what we don’t know about nutrition that hurts us, it is what we know for sure that turns out to be dead wrong.
—attributed to Victor Herbert, MD, JD
Abbreviations:
80HdG (8-hydroxydeoxyguanosine), ROS (reactive oxygen species)To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Translational ResearchAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Iron and the sex difference in heart disease risk.Lancet. 1981; 1: 1293-1294
- Are menstruating women protected from heart disease because of, or in spite of, estrogen? Relevance to the iron hypothesis.Am Heart J. 2003; 145: 190-194
- Moderate elevation of body iron level and increased risk of cancer occurrence and death.Int J Cancer. 1994; 56: 364-369
- Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.J Natl Cancer Inst. 2003; 95: 154-159
- Increased prevalence of the HFE C282Y hemochromatosis allele in women with breast cancer.Cancer Epidemiol Biomarkers Prev. 2004; 13: 205-212
- Iron and carcinogenesis.Redox Rep. 2002; 7: 189-197
- Low iron status and enhanced insulin sensitivity in lacto-ovo vegetarians.Br J Nutr. 2001; 86: 515-519
- Dietary iron intake and type 2 diabetes incidence in postmenopausal women.Diabetologia. 2004; 47: 185-194
- Body iron stores are associated with serum insulin and blood glucose concentrations. Population study in 1,013 eastern Finnish men.Diabetes Care. 1997; 20: 426-428
- Iron and infection.Best Pract Res Clin Haematol. 2002; 15: 411-426
- Iron and infection.Microbiol Rev. 1978; 42: 45-66
- Novel chelators for central nervous system disorders that involve alterations in the metabolism of iron and other metal ions.Ann N Y Acad Sci. 2004; 1012: 326-341
- Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer’s disease.J Med Genet. 2004; 41: 261-265
- Iron metabolism, free radicals, and oxidative injury.Biomed Pharmacother. 2001; 55: 333-339
- Safety aspects of iron in food.Ann Nutr Metab. 2001; 45: 91-101
- Direct detection and quantification of transition metal ions in human atherosclerotic plaques.Arterioscler Thromb Vasc Biol. 2004; 24: 1-7
- Iron depletion decreases lung injury after systemic complement activation [Abstract].Fed. Proc. 1986; 45: 452
- Nutritional iron restriction diminishes acute complement-dependent lung injury.Nutr Res. 1989; 9: 625-634
- Effect of nutritional iron deficiency on acute and chronic inflammation.Ann Rheum Dis. 1987; 46: 859-865
- Effect of iron deficiency on bleomycin-induced lung fibrosis in the hamster.Am Rev Respir Dis. 1988; 137: 85-89
- Iron depletion or chelation reduces ischemia/reperfusion-induced edema in gerbil brains.J Pediatr Surg. 1990; 25: 224-227
- Lowering of body iron stores by blood letting and oxidation resistance of serum lipoproteins.J Intern Med. 1995; 237: 161-168
- Iron-deficient diet reduces atherosclerotic lesions in apoE-deficient mice.Circulation. 1999; 99: 1222-1229
- Dietary iron restriction increases plaque stability in apolipoprotein-e-deficient mice.J Biomed Sci. 2003; 10: 510-517
- Beneficial effects of blood donation on high density lipoprotein concentration and the oxidative potential of low density lipoprotein.Atherosclerosis. 2002; 161: 395-402
- Inhibitory effect of dietary iron deficiency on inductions of putative preneoplastic lesions as well as 8-hydroxydeoxyguanosine in DNA and lipid peroxidation in the livers of rats caused by exposure to a choline-deficient L-amino acid defined diet.Carcinogenesis. 1992; 13: 1227-1233
- Serum aminotransferase levels as an indicator of the effectiveness of venesection for chronic hepatitis C.J Hepatol. 1995; 22: 268-271
- The onset of atherosclerotic lesion formation in hypercholesterolemic rabbits is delayed by iron depletion.FEBS Lett. 1999; 459: 218-222
- Near-iron deficiency-induced remission of gouty arthritis.Rheumatology (Oxford). 2003; 42: 1-6
- Effect of iron depletion on cardiovascular risk factors.Ann N Y Acad Sci. 2002; 967: 342-351
- A low-iron-available, polyphenol-enriched, carbohydrate-restricted diet to slow progression of diabetic nephropathy.Diabetes. 2003; 52: 1204-1209
- Cytokine signatures in atherosclerotic claudicants.J Surg Res. 2003; 111: 215-221
- Restored vulnerability of cultured endothelial cells to high glucose by iron replenishment.Biochem Biophys Res Commun. 2001; 289: 664-669
- Serum ferritin increases in hemorrhaged rats that develop acute lung injury.Inflammation. 2003; 27: 257-263
- Nutritional iron deprivation attenuates kainate-induced neurotoxicity in rats.Ann N Y Acad Sci. 2004; 1012: 94-114
- Effects of iron deprivation or chelation on DNA damage in experimental colitis.Int J Colorectal Dis. 2004; 19: 461-466
- Effect of iron overload and iron deficiency on atherosclerosis in the hypercholesterolemic rabbit.Arterioscler Thromb Vasc Biol. 1997; 17: 2638-2645
- Control of disease by selective iron depletion.Baillieres Clin Haematol. 1994; 7: 965-1000
- Iron-mediated cardiovascular injury.Vasc Med. 1999; 4: 93-99
- Effect of iron chelation on inflammatory joint disease.Ann Rheum Dis. 1987; 46: 327-333
- Iron as the malignant spirit in successful ageing.Ageing Res Rev. 2003; 2: 25-37
- The retardation of aging by caloric restriction.Exp Gerontol. 2003; 38: 1343-1351
- The Journal of Nutrition. Volume 18 July-December, 1939. Pages 1–13. Retarded growth, life span, ultimate body size and age changes in the albino rat after feeding diets restricted in calories.Nutr Rev. 1975; 33: 241-243
- Inhibition of iron absorption prolongs the life span of Drosophila.Mech Ageing Dev. 1993; 67: 227-237
- DNA Oxidative damage and life expectancy in houseflies.Proc Natl Acad Sci USA. 1994; 91: 12332-12335
- Oxidative DNA damage (8-hydroxydeoxyguanosine) and body iron status.Free Radic Biol Med. 2003; 35: 826-832
Article info
Publication history
Accepted:
October 7,
2004
Received:
July 8,
2004
Identification
Copyright
© 2004 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
