Research Article| Volume 20, ISSUE 9, P929-934, June 1935

The serum calcium in arthritis

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      The values for the mean and the standard deviation of the serum calcium in a group of 50 cases of rheumatoid arthritis were 10.218 ± 0.699 mg. per 100 c.c. These values were essentially the same as those found in control cases
      The values for the mean and the standard deviation of the serum calcium in a group of 50 cases of osteoarthritis were 9.986 ± 0.616 mg. per 100 c.c. The changes in the serum calcium in any individual are perhaps without direct clinical significance, but the trend in the group represents a statistically significant reduction in the mean calcium level. The reason for this change is not obvious. Its presence in osteoarthritis and absence in rheumatoid arthritis are further evidences that these two conditions represent separate clinical entities.
      This study of the serum calcium furnishes no evidence that hyperactivity of the parathyroid glands is a factor in the production of arthritis.
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