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- 1.1. Three phenol derivatives have been compared with iodine and four other drugs of common clinical usage in the presence of blood serum, vesicle fluid, and hide powder.
- 2.2. The fungicidal power of iodine as determined in water and broth suspensions was greatly reduced in suspensions of serum, vesicle fluid, and hide powder; that of n-hexyl resorcinol was reduced but the relative diminution was less than that of iodine; saturated solutions of chlorothymol failed to kill in the presence of proteins while thymol was effective only in the presence of hide powder; benzoic acid, salicylic acid and sodium thiosulphate were entirely ineffective in the protein suspensions, but sodium hypochlorite maintained its killing power in high concentrations.
- 3.3. Higher phenols have been found worthy of further clinical study in the treatment of fungus diseases.
- 4.4. A drug more specific in its action than those now available is needed.
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- The Fungicidal Power of Phenol Derivatives. I. Effect of Introducing Alkyl Groups and Halogens.J. Lab. & Clin. Med. 1934; 19: 1216
- Epidermomycosis at the University of California (Study III).Arch. Dermat. & Syph. 1933; 27: 12
- Prophylaxis of Ringworm of the Feet.J. A. M. A. 1931; 97: 453
Received: October 12, 1934With Lyle B. Kingery, M.D. and Roger J. Williams, Ph.D., D.Sc.
© 1935 Published by Elsevier Inc.