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Research Article| Volume 22, ISSUE 10, P1026-1031, July 1937

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Anaphylactoid reactions to colloidal sulphur in guinea pigs

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      Abstract

      • 1.
        1. Colloidal preparations of sulphur when administered intravenously in guinea pigs produce anaphylactoid reactions.
      • 2.
        2. Previous injections of sulphur apparently diminish the incidence and severity of the anaphylactoid response to sulphur.
      • 3.
        3. Differences in the aqueous and oleous preparations are pointed out.
      • 4.
        4. The lethal dose in guinea pigs is far in excess of the amounts recommended for clinical use.
      • 5.
        5. The anaphylactoid reaction is discussed briefly.
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