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Abstract
In ten individuals without thyroid disease and maintained on a low iodine diet; with
normal metabolic rates and normal whole blood iodine averaging 4.0 μg per cent, the
average serum iodine was 7.1 μg per cent. The serum iodine constituted, on an average,
95 per cent of the total blood iodine.
In ten patients with exophthalmic goiter, with an average basal metabolic rate of
plus 60 per cent, and maintained on a low iodine intake, the average blood iodine
was 10.0 μg per cent, the average serum iodine was 18.0 μg per cent. On an average,
95 per cent of the iodine of the blood was in the serum.
Following lipiodolization of ten patients without thyroid disease, the whole blood
iodine ranged from 18.5 to 3153.0 μg per cent, with the serum iodine fluctuating from
25.7 to 4,232.0. From 61 to 88 per cent, or on an average 75 per cent, of the total
iodine of the blood was in the serum.
In ten patients with exophthalmic goiter, with an average basal metabolic rate of
plus 35 per cent, while receiving Lugol's solution or potassium iodide by mouth, the
blood iodine concentration fluctuated from 15.2 to 107.0 μg per cent, with the serum
iodine concentration varying from 20.2 to 130.0. From 60 to 80 per cent, or at an
average 72 per cent, of the iodine of the blood was in the serum.
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References
- The Iodine Metabolism in Exophthalmic Goiter.Ann. Surg. 1938; 108: 574
- Beiträge zur Kenntnis des Jodstoffwechsels.Deutsches Arch. f. klin. Med. 1925; 147: 166
- Ueber den inneren Jodstoffwechsel bei primären Thyreotoxikosen (Primär-Basedow).Klin. Wchnschr. 1928; 7: 2287
- Blutjodstudien; die Blutjodfraktionen.Ztschr. f. klin. Med. 1938; 133: 513
- Iodine Metabolism and Thyroid Function.in: Oxford University Press, London1938: 100
- Iodine Metabolism and Thyroid Function.in: Oxford University Press, London1938: 377-378
- The Iodine Content of Hospital Foods.J. Am. Dietet. A. 1934; 10: 200
- Determination of Iodine in Biological Materials.Indust. & Engin. Chem., Anal. Ed. 1938; 10: 612
- The Intrapulmonic Absorption of Iodine.J. Pharmacol. & Exper. Therap. 1935; 53: 327
- The Comparative Iodine Content of Blood and Cerebrospinal Fluid.J. Lab. & Clin. Med. 1940; 25: 383
Article info
Publication history
Received:
February 28,
1940
Footnotes
☆This investigation was aided by a grant from the Comly Fund for Research of the Ohio State University.
Identification
Copyright
© 1940 Published by Elsevier Inc.
