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Abstract
The concentration of organic acid-soluble phosphorus in the blood cells is greatly
reduced during severe acidosis in subjects with adequate renal function, following
the ingestion of ammonium chloride, in diabetic coma, and in infants with profuse
diarrhea. The decrease is in the diphosphoglycerate fraction, which appears to be
one source of the increased phosphaturia that occurs in these conditions. High, normal,
or low concentrations of organic acid-soluble phosphorus in the blood cells may be
found during acidosis in nephritic subjects with low renal function, depending upon
different conditions present in individual cases. The changes of phosphorus distribution
are closely related to the state of other electrolytes in the blood, and they appear
to constitute a valuable index of the functional state of the labile phosphorus reserves
of the body.
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References
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© 1940 Published by Elsevier Inc.