MicroRNAs have emerged as novel and important regulators of translation. Besides their
biological significance, they are being investigated as potential biomarkers of physiological
and pathological states. This review article summarizes current investigations of
microRNAs as biomarkers in lung cancer. The promises and pitfalls of this exciting
new investigational avenue are highlighted.
Abbreviations:
CT (computed tomography), FFPE (formalin-fixed paraffin-embedded), RBC (red blood cell), RT-PCR (real-time polymerase chain reaction)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: January 28, 2011
Accepted:
December 29,
2010
Received in revised form:
December 23,
2010
Received:
December 4,
2010
Footnotes
Supported by research grants from the Buswell Foundation and the Thoracic Surgery Foundation for Research and Education, and by a Young Investigator Award from the Cancer and Leukemia Group B (CALGB) Foundation. Research support was also received from the Medical Prognosis Institute, Horsholm, Denmark.
Identification
Copyright
© 2011 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
