Neuroimaging combines multiple imaging modalities that allow the visualization and
study of the structure, function, pharmacology, and pathophysiology of the nervous
system. Over the last several decades, this field has seen remarkable developments,
with the work by Dandy
1
on ventriculography and pneumoencephalography in 1918 and 1919, the introduction
of cerebral angiography in 1927 by Egas Moniz,
2
,
3
the introduction of computerized axial tomography by Cormack and Hounsfield in the
early 1970s for which they won the 1979 Nobel Prize for Physiology or Medicine,
4
and around that same time the introduction of magnetic resonance imaging (MRI) by
Mansfield and Lauterbur for which they won the 2003 Nobel Prize for Physiology or
Medicine.
5
After these groundbreaking discoveries, continued technological and software developments
allowed for the advent of computed tomography angiography, magnetic resonance angiography
(MRA), functional MRI, and magnetoencephalography, among other techniques, further
expanding the array of medical applications covered. Cerebrovascular disease and other
disease entities such as Alzheimer's and Parkinson's can now be studied noninvasively
in-depth.To read this article in full you will need to make a payment
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References
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Article info
Publication history
Published online: December 18, 2015
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© 2015 Elsevier Inc. All rights reserved.
