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November 23, 2022

November 19, 2022

Risk Factors for Clonal Hematopoiesis of Indeterminate Potential and Mosaic Chromosomal Alterations

  • Yasminka A. Jakubek,
  • Alexander P. Reiner,
  • Michael C. Honigberg
Published online: November 19, 2022

November 16, 2022

Serum neurofilament light as a biomarker of vulnerability to a second mild traumatic brain injury

  • William T. O'Brien,
  • David K. Wright,
  • Ashley L.J.J. van Emmerik,
  • ...
  • Mastura Monif,
  • Sandy R. Shultz,
  • Stuart J. McDonald
Published online: November 16, 2022
Open Access

November 14, 2022

Arsenic trioxide sensitizes pancreatic cancer cells to gemcitabine through downregulation of the TIMP1/PI3K/AKT/mTOR axis

  • Zhenfeng Tian,
  • Ying Tan,
  • Xingyi Lin,
  • ...
  • Lijun Lin,
  • Guangsheng Ou,
  • Yinting Chen
Published online: November 14, 2022

Inhibition of PI3K/C/EBPβ axis in tolerogenic bone marrow-derived dendritic cells of NOD mice promotes Th17 differentiation and diabetes development

  • Chantal Guindi,
  • Farhan Ullah Khan,
  • Alexandre Cloutier,
  • ...
  • Patrick P. McDonald,
  • Denis Gris,
  • Abdelaziz Amrani
Published online: November 14, 2022

November 12, 2022

Non-canonical NF-κB contributes to endothelial pyroptosis and atherogenesis dependent on IRF-1

  • Xing Fan,
  • Qiannan Li,
  • Yiying Wang,
  • ...
  • Liang Sheng,
  • Anthony G. Passerini,
  • ChongXiu Sun
Published online: November 12, 2022

November 5, 2022

Clonal hematopoiesis and bone marrow inflammation

  • Xinshu Xie,
  • Meng Su,
  • Kehan Ren,
  • ...
  • Zhaofeng Li,
  • Yang Mei,
  • Peng Ji
Published online: November 05, 2022

Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation

  • Eisho Kanemitsu,
  • Xiangdong Zhao,
  • Keiko Iwaisako,
  • ...
  • Etsuro Hatano,
  • Shinji Uemoto,
  • Masatoshi Hagiwara
Published online: November 05, 2022
Open Access

Defining the sensitivity landscape of EGFR variants to tyrosine kinase inhibitors

  • Lei An,
  • Yueqiang Wang,
  • Guangyao Wu,
  • ...
  • Kongming Wu,
  • Shuqing Chen,
  • Hongen Xu
Published online: November 05, 2022
Open Access

November 3, 2022

Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias

  • STEFFEN POCKES,
  • MICHAEL A. WALTERS,
  • KAREN H. ASHE
Published online: November 03, 2022
Open Access

Disulfiram accelerates diabetic foot ulcer healing by blocking NET formation via suppressing the NLRP3/Caspase-1/GSDMD pathway

  • Shuofei Yang,
  • Yu Feng,
  • Liang Chen,
  • ...
  • Xiangjiang Guo,
  • Lan Zhang,
  • Guanhua Xue
Published online: November 03, 2022

October 30, 2022

Pathophysiological characterization of the townes mouse model for sickle cell disease

  • Juliana Alvarez-Argote,
  • Theresa A. Dlugi,
  • Teresa Sundararajan,
  • ...
  • Mary L. Faber,
  • William M. McKillop,
  • Jeffrey A. Medin
Published online: October 30, 2022

October 26, 2022

A CD36 transmembrane domain peptide interrupts CD36 interactions with membrane partners on macrophages and inhibits atherogenic functions

  • Wenxin Huang,
  • Renhao Li,
  • Jue Zhang,
  • Yiliang Cheng,
  • Devi P. Ramakrishnan,
  • Roy L. Silverstein
Published online: October 26, 2022

October 20, 2022

October 19, 2022

Expression and function of α4β7 integrin predict the success of vedolizumab treatment in inflammatory bowel disease

  • Ines Schneider,
  • Clarissa Allner,
  • Laura Mühl,
  • ...
  • Britta Siegmund,
  • Markus F. Neurath,
  • Sebastian Zundler
Published online: October 19, 2022
Open Access

October 15, 2022

Nedd4L suppression in lung fibroblasts facilitates pathogenesis of lung fibrosis

  • Shuang Li,
  • Qinmao Ye,
  • Jianxin Wei,
  • ...
  • Jeffrey C Horowitz,
  • Jing Zhao,
  • Yutong Zhao
Published online: October 15, 2022

October 12, 2022

PFKFB3 mediates tubular cell death in cisplatin nephrotoxicity by activating CDK4

  • Lu Wen,
  • Qingqing Wei,
  • Man J. Livingston,
  • ...
  • Ying Li,
  • Yuqing Huo,
  • Zheng Dong
Published online: October 12, 2022

October 9, 2022

Long-read sequencing reveals oncogenic mechanism of HPV-human fusion transcripts in cervical cancer

  • Min Liu,
  • Zhiqiang Han,
  • Yong Zhi,
  • ...
  • Xuejun Wen,
  • Qingfeng Zhang,
  • Fang Li
Published online: October 09, 2022

September 22, 2022

Pin1 and Alzheimer's disease

  • James S. Malter
Published online: September 22, 2022

September 20, 2022

Inflammasome signaling in colorectal cancer

  • Bhesh Raj Sharma,
  • Thirumala-Devi Kanneganti
Published online: September 20, 2022

September 12, 2022

Development of strategies for community engaged research dissemination by basic scientists: a case study

  • Elizabeth C. Stewart,
  • Jamaine S. Davis,
  • Treniqka S. Walters,
  • ...
  • Ira Baxter,
  • Sondrea Tolbert,
  • Jennifer Cunningham Erves
Published online: September 12, 2022

September 9, 2022

Establishment of a human 3D pancreatic adenocarcinoma model based on a patient-derived extracellular matrix scaffold

  • Francesca Sensi,
  • Edoardo D'angelo,
  • Andrea Biccari,
  • ...
  • Gaya Spolverato,
  • Salvatore Pucciarelli,
  • Marco Agostini
Published online: September 09, 2022
Open Access

September 8, 2022

Tumor suppressor role of RBM22 in prostate cancer acting as a dual-factor regulating alternative splicing and transcription of key oncogenic genes

  • Juan M. Jiménez-Vacas,
  • Antonio J. Montero-Hidalgo,
  • Enrique Gómez-Gómez,
  • ...
  • Justo P. Castaño,
  • Manuel D. Gahete,
  • Raul M. Luque
Published online: September 08, 2022
Open Access

September 5, 2022

SIK2 protects against renal tubular injury and the progression of diabetic kidney disease

  • Bingyao Liu,
  • Linlin Zhang,
  • Hang Yang,
  • Xinyu Chen,
  • Hongting Zheng,
  • Xiaoyu Liao
Published online: September 05, 2022
Open Access

September 4, 2022

Inflammasome activation in traumatic brain injury and Alzheimer's disease

  • Nathan H. Johnson,
  • Juan Pablo de Rivero Vaccari,
  • Helen M. Bramlett,
  • Robert W. Keane,
  • W. Dalton Dietrich
Published online: September 04, 2022
Open Access

September 2, 2022

Clonal hematopoiesis of indeterminate potential and cardiovascular disease

  • Seyedmohammad Saadatagah,
  • Christie M. Ballantyne
Published online: September 02, 2022

August 28, 2022

Targeting tumor-associated MUC1 overcomes anoikis-resistance in pancreatic cancer

  • Mukulika Bose,
  • Alexa Sanders,
  • Chandrav De,
  • ...
  • Bhaskar Mitra,
  • Cory Brouwer,
  • Pinku Mukherjee
Published online: August 28, 2022
Open Access

Connectome-based biophysics models of Alzheimer’s disease diagnosis and prognosis

  • Justin Torok,
  • Chaitali Anand,
  • Parul Verma,
  • Ashish Raj
Published online: August 28, 2022
Open Access

August 27, 2022

The NLRP3 inflammasome fires up heme-induced inflammation in hemolytic conditions

  • Suruchi Salgar,
  • Beatriz E Bolívar,
  • Jonathan M Flanagan,
  • Shaniqua J Anum,
  • Lisa Bouchier-Hayes
Published online: August 27, 2022

August 11, 2022

COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy

  • Deepak Kumar,
  • Sonam Verma,
  • Indira U. Mysorekar
Published online: August 11, 2022

August 8, 2022

Protein glycosylation in urine as a biomarker of diseases

  • Mingming Xu,
  • Arthur Yang,
  • Jun Xia,
  • ...
  • Zhenyu Ye,
  • Junfeng Ma,
  • Shuang Yang
Published online: August 08, 2022

NLRP3 inflammasome in neurodegenerative disease

  • Faith L. Anderson,
  • Karl E. Biggs,
  • Brynn E. Rankin,
  • Matthew C. Havrda
Published online: August 08, 2022

August 6, 2022

NLRP3-mediated inflammation in cardio-oncology: sterile yet harmful

  • Adolfo G. Mauro,
  • Eleonora Mezzaroma,
  • Stefano Toldo,
  • ...
  • Antonio Abbate,
  • W. Gregory Hundley,
  • Fadi N. Salloum
Published online: August 06, 2022

Radiation combined with KRAS-MEK inhibitors enhances anticancer immunity in KRAS-mutated tumor models

  • Yawen Zheng,
  • Yanan Liu,
  • Fang Zhang,
  • ...
  • Meili Sun,
  • Yuping Sun,
  • Ligang Xing
Published online: August 06, 2022
Open Access

Compartmental model describing the physiological basis for the HepQuant SHUNT test

  • Michael P. McRae,
  • Steve M. Helmke,
  • James R. Burton Jr.,
  • Gregory T. Everson
Published online: August 06, 2022

August 1, 2022

Role and mechanism of miR-335-5p in the pathogenesis and treatment of polycystic ovary syndrome

  • Shanshan Zhang,
  • Yajing Liu,
  • Mingming Wang,
  • ...
  • Slawomir Wolczynski,
  • Nafis A Rahman,
  • Xiangdong Li
Published online: August 01, 2022

July 31, 2022

A missense mutation in lectin domain of thrombomodulin causing functional deficiency

  • Ma Jiewen,
  • Tao yanyi,
  • Feng Yuanzheng,
  • ...
  • Hu Bei,
  • Hu Yu,
  • Liang V. Tang
Published online: July 31, 2022

July 30, 2022

Inflammasomes as mediators of inflammation in HIV-1 infection

  • Alice K. Min,
  • Trinisia Fortune,
  • Natalia Rodriguez,
  • Esha Hedge,
  • Talia H. Swartz
Published online: July 30, 2022

July 25, 2022

Single-cell RNA sequencing in the context of neuropathic pain: progress, challenges, and prospects

  • Lei Chen,
  • Yunze Li,
  • Lina Zhu,
  • Haifei Jin,
  • Xianhui Kang,
  • Zhiying Feng
Published online: July 25, 2022
Open Access

July 23, 2022

Spliceosomic dysregulation unveils NOVA1 as a candidate actionable therapeutic target in pancreatic neuroendocrine tumors

  • Sergio Pedraza-Arevalo,
  • Emilia Alors-Pérez,
  • Ricardo Blázquez-Encinas,
  • ...
  • Alejandro Ibáñez-Costa,
  • Raúl M. Luque,
  • Justo P. Castaño
Published online: July 23, 2022

July 17, 2022

July 3, 2022

Mechanism of action of IC 100, a humanized IgG4 monoclonal antibody targeting apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)

  • Juan Pablo de Rivero Vaccari,
  • Carsten Mim,
  • Roey Hadad,
  • Brianna Cyr,
  • Thorunn Anna Stefansdottir,
  • Robert W. Keane
Published online: July 03, 2022
Open Access

July 1, 2022

Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration

  • Elena Porcù,
  • Francesca Maule,
  • Lorenzo Manfreda,
  • ...
  • Giampietro Viola,
  • Elena Rampazzo,
  • Luca Persano
Published online: July 01, 2022

June 16, 2022

Inhibition of alkaline phosphatase impairs dyslipidemia and protects mice from atherosclerosis

  • Laurence Bessueille,
  • Lynn Kawtharany,
  • Thibaut Quillard,
  • ...
  • Emmanuelle Canet-soulas,
  • Jose luis Millan,
  • David Magne
Published online: June 16, 2022

June 14, 2022

SERPINA5 may promote the development of preeclampsia by disruption of the uPA/uPAR pathway

  • Yan Long,
  • Shanshui Zeng,
  • Fei Gao,
  • ...
  • Min Jiang,
  • Gendie E. Lash,
  • Hongling Yang
Published online: June 14, 2022
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