July 2021

Contents
Published in issue: July 2021
i

Masthead
Published in issue: July 2021
ii

Editorial Advisory Board
Published in issue: July 2021
iii-iv

Author Guidelines
Published in issue: July 2021
v-vii

Commentary

How clinicians may use tests of hepatic function now and in the future
• T. Tara Ghaziani,
• Paul Y. Kwo
Published online: April 04, 2021
p1-4

Original Research Article

The within-individual reproducibility of the disease severity index from the HepQuant SHUNT test of liver function and physiology
• James R. Burton Jr.,
• Steven Helmke,
• Shannon Lauriski,
• John Kittelson,
• Gregory T. Everson
Published online: January 02, 2021
p5-15

Mechanism of IL-6-related spontaneous atrial fibrillation after coronary artery grafting surgery: IL-6 knockout mouse study and human observation
• Yisi Liu,
• Fangqin Wu,
• Ying Wu,
• ...
• Ying Deng,
• Dianxu Ren,
• Haibo Zhao
Published online: January 16, 2021
p16-31

Histone citrullination as a novel biomarker and target to inhibit progression of abdominal aortic aneurysms
• Wolf Eilenberg,
• Branislav Zagrapan,
• Sonja Bleichert,
• ...
• Ihor Huk,
• Christoph Neumayer,
• Christine Brostjan
Published online: February 08, 2021
p32-46
Open Access

Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling
• Pengyu Jia,
• Nan Wu,
• Huimin Yang,
• Yuxuan Guo,
• Xiaofan Guo,
• Yingxian Sun
Published online: February 08, 2021
p47-61

Toll-like receptor 2 signaling deficiency in cardiac cells ameliorates Ang II-induced cardiac inflammation and remodeling
• Shiju Ye,
• Ke Lin,
• Gaojun Wu,
• ...
• Weijian Huang,
• Yi Wang,
• Guang Liang
Published online: February 27, 2021
p62-76

A model based on the quantification of complement C4c, CYFRA 21-1 and CRP exhibits high specificity for the early diagnosis of lung cancer
• Daniel Ajona,
• Ana Remirez,
• Cristina Sainz,
• ...
• Pierre P Massion,
• Luis M Montuenga,
• Ruben Pio
Published online: February 19, 2021
p77-91
Open Access

Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients
• Yufeng Wu,
• Zhensheng Liu,
• Dongfang Tang,
• ...
• David C. Christiani,
• Qiming Wang,
• Qingyi Wei
Published online: January 02, 2021
p92-103

Activation of p21 limits acute lung injury and induces early senescence after acid aspiration and mechanical ventilation
• Jorge Blázquez-Prieto,
• Covadonga Huidobro,
• Inés López-Alonso,
• ...
• Manuel Serrano,
• Jacob I Sznajder,
• Guillermo M Albaiceta
Published online: January 26, 2021
p104-116

Circulating chaperones in patients with aortic valve stenosis undergoing TAVR: impact of concomitant chronic kidney disease
• Adem Aksoy,
• Baravan Al-Kassou,
• Muntadher Al Zaidi,
• ...
• Sebastian Zimmer,
• Georg Nickenig,
• Vedat Tiyerili
Published online: March 05, 2021
p117-126

Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension
• Keizo Hiraishi,
• Lin Hai Kurahara,
• Jianlin Feng,
• ...
• Lixia Yue,
• Ryuji Inoue,
• Katsuya Hirano
Published online: March 07, 2021
p127-143
Open Access

Review Article

Influence of immunomodulatory drugs on the gut microbiota
• Inessa Cohen,
• William E. Ruff,
• Erin E. Longbrake
Published online: January 27, 2021
p144-161

Long and short non-coding RNA and radiation response: a review
• Jared M. May,
• Michelle Bylicky,
• Sunita Chopra,
• C. Norman Coleman,
• Molykutty J. Aryankalayil
Published online: February 11, 2021
p162-179
Open Access

Information for Readers
Published in issue: July 2021
CO3

Contents
Published in issue: July 2021
CO4